Metabolite of the pesticide DDT and incident type 2 diabetes in urban India.

ABSTRACT: BACKGROUND:Previous epidemiological studies, largely conducted in high-income countries and cross-sectional, have suggested a relatively strong association between exposure to dichlorodiphenyldichloroethylene (DDE), a metabolite of the pesticide dichlorodiphenyltrichloroethane (DDT), and type 2 diabetes. DDT is widely used in India and the prevalence of type 2 diabetes there is increasing, but the association between these factors has not been explored to date. OBJECTIVE:The objective was to estimate the association of the p,p' isomer of DDE with incident type 2 diabetes in India. METHODS:A nested case-control study was conducted in a representative prospective cohort of adults from two cities in India. Participants were enrolled in 2010-11 (n = 12,271) and followed for annual assessment o

SUBMITTER: Jaacks LM 

PROVIDER: S-EPMC6860016 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature