A circadian output center controlling feeding:fasting rhythms in Drosophila.

ABSTRACT: Circadian rhythms allow animals to coordinate behavioral and physiological processes with respect to one another and to synchronize these processes to external environmental cycles. In most animals, circadian rhythms are produced by core clock neurons in the brain that generate and transmit time-of-day signals to downstream tissues, driving overt rhythms. The neuronal pathways controlling clock outputs, however, are not well understood. Furthermore, it is unclear how the central clock modulates multiple distinct circadian outputs. Identifying the cellular components and neuronal circuitry underlying circadian regulation is increasingly recognized as a critical step in the effort to address health pathologies linked to circadian disruption, including heart disease and metabolic disorders. H

SUBMITTER: Dreyer AP 

PROVIDER: S-EPMC6860455 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature