An inflammatory profile linked to increased suicide risk.

ABSTRACT:

Background

Suicide risk assessments are often challenging for clinicians, and therefore, biological markers are warranted as guiding tools in these assessments. Suicidal patients display increased cytokine levels in peripheral blood, although the composite inflammatory profile in the subjects is still unknown. It is also not yet established whether certain inflammatory changes are specific to suicidal subjects. To address this, we measured 45 immunobiological factors in peripheral blood and identified the biological profiles associated with cross-diagnostic suicide risk and depression, respectively.

Methods

Sixty-six women with mood and anxiety disorders underwent computerized adaptive testing for mental health, assessing depression and suicide risk. Weighted correlation net

SUBMITTER: Keaton SA 

PROVIDER: S-EPMC6860980 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature