Genus-wide Yersinia core-genome multilocus sequence typing for species identification and strain characterization.

ABSTRACT: The genus Yersinia comprises species that differ widely in their pathogenic potential and public-health significance. Yersinia pestis is responsible for plague, while Yersinia enterocolitica is a prominent enteropathogen. Strains within some species, including Y. enterocolitica, also vary in their pathogenic properties. Phenotypic identification of Yersinia species is time-consuming, labour-intensive and may lead to incorrect identifications. Here, we developed a method to automatically identify and subtype all Yersinia isolates from their genomic sequence. A phylogenetic analysis of Yersinia isolates based on a core subset of 500 shared genes clearly demarcated all existing Yersinia species and uncovered novel, yet undefined Yersi

SUBMITTER: Savin C 

PROVIDER: S-EPMC6861861 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature