Haplotype Networking of GWAS Hits for Citrulline Variation Associated with the Domestication of Watermelon.

ABSTRACT: Watermelon is a good source of citrulline, a non-protein amino acid. Citrulline has several therapeutic and clinical implications as it produces nitric oxide via arginine. In plants, citrulline plays a pivotal role in nitrogen transport and osmoprotection. The purpose of this study was to identify single nucleotide polymorphism (SNP) markers associated with citrulline metabolism using a genome-wide association study (GWAS) and understand the role of citrulline in watermelon domestication. A watermelon collection consisting of 187 wild, landraces, and cultivated accessions was used to estimate citrulline content. An association analysis involved a total of 12,125 SNPs with a minor allele frequency (MAF) >0.05 in understanding the population structure and phylogeny in light of citrulline acc

SUBMITTER: Joshi V 

PROVIDER: S-EPMC6862219 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature