Dietary acid load and bone turnover during long-duration spaceflight and bed rest.

ABSTRACT:

Background

Bed rest studies document that a lower dietary acid load is associated with lower bone resorption.

Objective

We tested the effect of dietary acid load on bone metabolism during spaceflight.

Design

Controlled 4-d diets with a high or low animal protein-to-potassium (APro:K) ratio (High and Low diets, respectively) were given to 17 astronauts before and during spaceflight. Each astronaut had 1 High and 1 Low diet session before flight and 2 High and 2 Low sessions during flight, in addition to a 4-d session around flight day 30 (FD30), when crew members were to consume their typical in-flight intake. At the end of each session, blood and urine samples were collected. Calcium, total protein, energy, and sodium were maintained in each crew member's preflight an

SUBMITTER: Zwart SR 

PROVIDER: S-EPMC6862931 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature