Impact of age at diagnosis on racial disparities in endometrial cancer patients.

ABSTRACT:

Introduction

Although black patients with endometrial cancer (EC) have worse survival compared with white patients, the interaction between age/race has not been examined. The primary objective was to evaluate the impact of age at diagnosis on racial disparities in disease presentation and outcome in EC.

Methods

We evaluated women diagnosed with EC between 1991 and 2010 from the Surveillance, Epidemiology, and End Results. Mutation status for TP53 or PTEN, or with the aggressive integrative, transcript-based, or somatic copy number alteration-based molecular subtype were acquired from the Cancer Genome Atlas. Logistic regression model was used to estimate the interaction between age and race on histology. Cox regression model was used to estimate the interaction between age

SUBMITTER: Tarney CM 

PROVIDER: S-EPMC6863162 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature