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Skeletal Muscle Atrophy: Discovery of Mechanisms and Potential Therapies.

ABSTRACT: Skeletal muscle atrophy proceeds through a complex molecular signaling network that is just beginning to be understood. Here, we discuss examples of recently identified molecular mechanisms of muscle atrophy and how they highlight an immense need and opportunity for focused biochemical investigations and further unbiased discovery work.

SUBMITTER: Ebert SM 

PROVIDER: S-EPMC6863373 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Skeletal Muscle Atrophy: Discovery of Mechanisms and Potential Therapies.

Ebert Scott M SM   Al-Zougbi Asma A   Bodine Sue C SC   Adams Christopher M CM  

Physiology (Bethesda, Md.) 20190701 4

Skeletal muscle atrophy proceeds through a complex molecular signaling network that is just beginning to be understood. Here, we discuss examples of recently identified molecular mechanisms of muscle atrophy and how they highlight an immense need and opportunity for focused biochemical investigations and further unbiased discovery work. ...[more]

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