Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial.

ABSTRACT:

Objective

To determine whether an injection of platelet rich plasma improves outcomes after acute Achilles tendon rupture.

Design

Randomised, placebo controlled, two arm, parallel group, participant and assessor masked, superiority trial.

Setting

Secondary care trauma units across 19 hospitals in the United Kingdom's health service.

Participants

Recruitment commenced in July 2015 and follow-up was completed in March 2018. 230 adults aged 18 years and over were included, with acute Achilles tendon rupture presenting within 12 days of injury and managed with non-surgical treatment. Exclusions were injury at the insertion or musculotendinous junction, major leg injury or deformity, diabetes mellitus, platelet or haematological disorder, systemic corticosteroids, a

SUBMITTER: Keene DJ 

PROVIDER: S-EPMC6863552 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature