Molecular dynamics investigations for the prediction of molecular interaction of cauliflower mosaic virus transmission helper component protein complex with Myzus persicae stylet's cuticular protein and its docking studies with annosquamosin-A encapsulated in nano-porous Silica.

ABSTRACT: Large numbers of bioactive natural products from plant species such as alkaloids, phenolics, terpenoids etc. are remaining unexplored for their potential as plant protective agents as inhibitors for viral and other pathogenic infections of plant. Myzus aphids are important plant pests and vectors for several plant viruses. Cauliflower mosaic virus (CaMV) belongs to the plant virus family Caulimoviridae which is transmitted "non-circulative" from plant to plant through an interaction with aphid insect vectors. This viral transmission process most likely involves a protein-protein binding interaction between aphid stylet receptor cuticular protein and viral proteins namely, CaMV aphid transmission Helper Component protein and virion associated protein. Aphid stylets are made of cuticle and l

SUBMITTER: Sharmila DJS 

PROVIDER: S-EPMC6864000 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature