Effect of right ventricular pacing on left ventricular systolic function in patients with Tetralogy of Fallot.

ABSTRACT:

Background

Prevalence of pacemaker-induced cardiomyopathy (PICM) in adults with congenital heart disease is unknown. Tetralogy of Fallot (TOF) is a common diagnosis in the adult congenital heart disease population, and the purpose of this study was to determine association between frequent right ventricular (RV) pacing and temporal decrease in left ventricular ejection fraction (LVEF) from pre-implantation to 2-years post-implantation (LVEF_post-pre) in TOF patients.

Methods

We studied TOF patients that received RV leads only (N = 51) and a reference group of 7 patients with atrial pacing or biventricular pacing. We defined PICM as a ≥10% decrease in LVEF resulting in LVEF <50%. Linear regression was used to assess relationship between frequent RV pacing (≤20%, 21-

SUBMITTER: Egbe AC 

PROVIDER: S-EPMC6864126 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature