Association of Chorioamnionitis With Bronchopulmonary Dysplasia Among Preterm Infants: A Systematic Review, Meta-analysis, and Metaregression.

ABSTRACT:

Importance

Bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurity, remains one of the major and most common complications of very preterm birth. Insight into factors associated with the pathogenesis of BPD is key to improving its prevention and treatment.

Objective

To perform a systematic review, meta-analysis, and metaregression of clinical studies exploring the association between chorioamnionitis (CA) and BPD in preterm infants.

Data sources

PubMed and Embase were searched without language restriction (last search, October 1, 2018). Key search terms included bronchopulmonary dysplasia, chorioamnionitis, and risk factors.

Study selection

Included studies were peer-reviewed studies examining preterm (<37 weeks' gestation) or very low-birth-wei

SUBMITTER: Villamor-Martinez E 

PROVIDER: S-EPMC6865274 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature