Parcellation of the human hippocampus based on gray matter volume covariance: Replicable results on healthy young adults.

ABSTRACT: The hippocampus is a key brain region that participates in a range of cognitive and affective functions, and is involved in the etiopathogenesis of numerous neuropsychiatric disorders. The structural complexity and functional diversity of the hippocampus suggest the existence of structural and functional subdivisions within this structure. For the first time, we parcellated the human hippocampus with two independent data sets, each of which consisted of 198 T1-weighted structural magnetic resonance imaging (sMRI) images of healthy young subjects. The method was based on gray matter volume (GMV) covariance, which was quantified by a bivariate voxel-to-voxel linear correlation approach, as well as a multivariate masked independent component analysis approach. We subsequently interrogated the

SUBMITTER: Ge R 

PROVIDER: S-EPMC6865476 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature