Activation-based association profiles differentiate network roles across cognitive loads.

ABSTRACT: Working memory (WM) is a complex and pivotal cognitive system underlying the performance of many cognitive behaviors. Although individual differences in WM performance have previously been linked to the blood oxygenation level-dependent (BOLD) response across several large-scale brain networks, the unique and shared contributions of each large-scale brain network to efficient WM processes across different cognitive loads remain elusive. Using a WM paradigm and functional magnetic resonance imaging (fMRI) from the Human Connectome Project, we proposed a framework to assess the association and shared-association strength between imaging biomarkers and behavioral scales. Association strength is the capability of individual brain regions to modulate WM performance and shared-association streng

SUBMITTER: Zuo N 

PROVIDER: S-EPMC6865538 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature