Connectome-based model predicts individual differences in propensity to trust.

ABSTRACT: Trust constitutes a fundamental basis of human society and plays a pivotal role in almost every aspect of human relationships. Although enormous interest exists in determining the neuropsychological underpinnings of a person's propensity to trust utilizing task-based fMRI; however, little progress has been made in predicting its variations by task-free fMRI based on whole-brain resting-state functional connectivity (RSFC). Here, we combined a one-shot trust game with a connectome-based predictive modeling approach to predict propensity to trust from whole-brain RSFC. We demonstrated that individual variations in the propensity to trust were primarily predicted by RSFC rooted in the functional integration of distributed key nodes-caudate, amygdala, lateral prefrontal cortex, temporal-pariet

SUBMITTER: Lu X 

PROVIDER: S-EPMC6865671 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature