Analysis of brain subnetworks within the context of their whole-brain networks.

ABSTRACT: Analyzing the structure and function of the brain from a network perspective has increased considerably over the past two decades, with regional subnetwork analyses becoming prominent in the recent literature. However, despite the fact that the brain, as a complex system of interacting subsystems (i.e., subnetworks), cannot be fully understood by analyzing its constituent parts as independent elements, most studies extract subnetworks from the whole and treat them as independent networks. This approach entails neglecting their interactions with other brain regions and precludes identifying potential compensatory mechanisms outside the analyzed subnetwork. In this study, using simulated and empirical data, we show that the analysis of brain subnetworks within the context of their whole-brai

SUBMITTER: Bahrami M 

PROVIDER: S-EPMC6865778 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature