Association of Obesity With Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy.

ABSTRACT:

Importance

Patients with hypertrophic cardiomyopathy (HCM) are prone to body weight increase and obesity. Whether this predisposes these individuals to long-term adverse outcomes is still unresolved.

Objective

To describe the association of body mass index (BMI, calculated as weight in kilograms divided by height in meters squared) with long-term outcomes in patients with HCM in terms of overall disease progression, heart failure symptoms, and arrhythmias.

Design, setting, and participants

In this cohort study, retrospective data were analyzed from the ongoing prospective Sarcomeric Human Cardiomyopathy Registry, an international database created by 8 high-volume HCM centers that includes more than 6000 patients who have been observed longitudinally for decades. Recor

SUBMITTER: Fumagalli C 

PROVIDER: S-EPMC6865784 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature