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Multimodal neuroimaging analysis reveals age-associated common and discrete cognitive control constructs.


ABSTRACT: The aims of this study were to determine which cognitive control functions are most sensitive to cross-sectional age differences and to identify neural features in different neuroimaging modalities that associated cognitive control function across the adult lifespan. We employed a joint independent component analysis (jICA) approach to obtain common networks among three different brain-imaging modalities (i.e., structural MRI, resting-state functional MRI, and diffusion tensor imaging) in relation to the cognitive control function. We differentiated three distinct cognitive constructs: one common (across inhibition, shifting, and updating) and two specific (shifting, updating) factors. These common/specific constructs were transformed from three original performance indexes: (a) stop-signa

SUBMITTER: Yang MH 

PROVIDER: S-EPMC6865786 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature