Stepwise functional connectivity reveals altered sensory-multimodal integration in medication-naive adults with attention deficit hyperactivity disorder.

ABSTRACT: Neuroimaging studies indicate that children with attention-deficit/hyperactivity disorder (ADHD) present alterations in several functional networks of the sensation-to-cognition spectrum. These alterations include functional overconnectivity within sensory regions and underconnectivity between sensory regions and neural hubs supporting higher order cognitive functions. Today, it is unknown whether this same pattern of alterations persists in adult patients with ADHD who had never been medicated for their condition. The aim of the present study was to assess whether medication-naïve adults with ADHD presented alterations in functional networks of the sensation-to-cognition spectrum. Thirty-one medication-naïve adults with ADHD and twenty-two healthy adults underwent resting-state functional

SUBMITTER: Pretus C 

PROVIDER: S-EPMC6865796 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature