Age-Related Differences in the Noninvasive Evaluation for Possible Coronary Artery Disease: Insights From the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Trial.

ABSTRACT:

Importance

Although cardiovascular (CV) disease represents the leading cause of morbidity and mortality that increases with age, the best noninvasive test to identify older patients at risk for CV events remains unknown.

Objective

To determine whether the prognostic utility of anatomic vs functional testing varies based on patient age.

Design, setting, and participants

Prespecified analysis of the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) study, which used a pragmatic comparative effectiveness design. Participants were enrolled from 193 sites across North America and comprised outpatients without known coronary artery disease (CAD) but with symptoms suggestive of CAD. Data were analyzed between October 2018 and April 2019.

Interve

SUBMITTER: Lowenstern A 

PROVIDER: S-EPMC6865842 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature