Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres.

ABSTRACT:

Objective

To determine the relation between age and troponin level and its prognostic implication.

Design

Retrospective cohort study.

Setting

Five cardiovascular centres in the UK National Institute for Health Research Health Informatics Collaborative (UK-NIHR HIC).

Participants

257 948 consecutive patients undergoing troponin testing for any clinical reason between 2010 and 2017.

Main outcome measure

All cause mortality.

Results

257 948 patients had troponin measured during the study period. Analyses on troponin were performed using the peak troponin level, which was the highest troponin level measured during the patient's hospital stay. Troponin levels were standardised as a multiple of each laboratory's 99th centile of the upper limit of normal

SUBMITTER: Kaura A 

PROVIDER: S-EPMC6865859 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature