Action and semantic tool knowledge - Effective connectivity in the underlying neural networks.

ABSTRACT: Evidence from neuropsychological and imaging studies indicate that action and semantic knowledge about tools draw upon distinct neural substrates, but little is known about the underlying interregional effective connectivity. With fMRI and dynamic causal modeling (DCM) we investigated effective connectivity in the left-hemisphere (LH) while subjects performed (i) a function knowledge and (ii) a value knowledge task, both addressing semantic tool knowledge, and (iii) a manipulation (action) knowledge task. Overall, the results indicate crosstalk between action nodes and semantic nodes. Interestingly, effective connectivity was weakened between semantic nodes and action nodes during the manipulation task. Furthermore, pronounced modulations of effective connectivity within the fronto-parieta

SUBMITTER: Kleineberg NN 

PROVIDER: S-EPMC6866288 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature