Impact of different intensities of intermittent theta burst stimulation on the cortical properties during TMS-EEG and working memory performance.

ABSTRACT: Intermittent theta burst stimulation (iTBS) is a noninvasive brain stimulation technique capable of increasing cortical excitability beyond the stimulation period. Due to the rapid induction of modulatory effects, prefrontal application of iTBS is gaining popularity as a therapeutic tool for psychiatric disorders such as depression. In an attempt to increase efficacy, higher than conventional intensities are currently being applied. The assumption that this increases neuromodulatory may be mechanistically false for iTBS. This study examined the influence of intensity on the neurophysiological and behavioural effects of iTBS in the prefrontal cortex. Sixteen healthy participants received iTBS over prefrontal cortex at either 50, 75 or 100% resting motor threshold in separate sessions. Singl

SUBMITTER: Chung SW 

PROVIDER: S-EPMC6866298 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature