The optimistic brain: Trait optimism mediates the influence of resting-state brain activity and connectivity on anxiety in late adolescence.

ABSTRACT: As a hot research topic in the field of psychology and psychiatry, trait optimism reflects the tendency to expect positive outcomes in the future. Consistent evidence has demonstrated the role of trait optimism in reducing anxiety among different populations. However, less is known about the neural bases of trait optimism and the underlying mechanisms for how trait optimism protects against anxiety in the healthy brain. In this investigation, we examined these issues in 231 healthy adolescent students by assessing resting-state brain activity (i.e., fractional amplitude of low-frequency fluctuations, fALFF) and connectivity (i.e., resting-state functional connectivity, RSFC). Whole-brain correlation analyses revealed that higher levels of trait optimism were linked with decreased fALFF in

SUBMITTER: Wang S 

PROVIDER: S-EPMC6866307 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature