Multilevel convergence of interoceptive impairments in hypertension: New evidence of disrupted body-brain interactions.

ABSTRACT: Interoception, the sensing of visceral body signals, involves an interplay between neural and autonomic mechanisms. Clinical studies into this domain have focused on patients with neurological and psychiatric disorders, showing that damage to relevant brain mechanisms can variously alter interoceptive functions. However, the association between peripheral cardiac-system alterations and neurocognitive markers of interoception remains poorly understood. To bridge this gap, we examined multidimensional neural markers of interoception in patients with early stage of hypertensive disease (HTD) and healthy controls. Strategically, we recruited only HTD patients without cognitive impairment (as shown by neuropsychological tests), brain atrophy (as assessed with voxel-based morphometry), or white

SUBMITTER: Yoris A 

PROVIDER: S-EPMC6866355 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature