Development of short-range white matter in healthy children and adolescents.

ABSTRACT: Neural communication is facilitated by intricate networks of white matter (WM) comprised of both long and short range connections. The maturation of long range WM connections has been extensively characterized, with projection, commissural, and association tracts showing unique trajectories with age. There, however, remains a limited understanding of age-related changes occurring within short range WM connections, or U-fibers. These connections are important for local connectivity within lobes and facilitate regional cortical function and greater network economy. Recent studies have explored the maturation of U-fibers primarily using cross-sectional study designs. Here, we analyzed diffusion tensor imaging (DTI) data for healthy children and adolescents in both a cross-sectional (n = 78; m

SUBMITTER: Oyefiade AA 

PROVIDER: S-EPMC6866408 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature