Connectivity of the ventral visual cortex is necessary for object recognition in patients.

ABSTRACT: The functional profiles of regions in the ventral occipital-temporal cortex (VTC), a critical region for object visual recognition, are associated with the VTC connectivity patterns to nonvisual regions relevant to the corresponding object domain. However, whether and how whole-brain connections affect recognition behavior remains untested. We directly examined the necessity of VTC connectivity in object recognition behavior by testing 82 patients whose lesion spared relevant VTC regions but affected various white matter (WM) tracts and other regions. In these patients, we extracted the whole-brain anatomical connections of two VTC domain-selective (large manmade objects and animals) clusters with probabilistic tractography, and examined whether such connectivity pattern can predict recogn

SUBMITTER: Li Y 

PROVIDER: S-EPMC6866505 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature