Clinical characteristics of cognitive impairment in patients with Parkinson's disease and its related pattern in ¹⁸ F-FDG PET imaging.

ABSTRACT: This study aimed to characterize the clinical features and the related cerebral glucose metabolism pattern of cognitive impairments in Parkinson's disease (PD) with positron emission tomography (PET) imaging. We recruited 168 PD patients and 100 age-matched healthy controls of similar education and gender distribution. All of those enrolled underwent clinical assessment including the unified Parkinson's disease rating scale motor score, Hoehn and Yahr scale, and comprehensive neuropsychological tests including domains of executive function, attention, memory, visuospatial function, and language. Demographics and the results of cognitive measures were compared between patients and healthy controls. Cognition status was classified as PD patients with dementia (PD-D), PD patients with mild co

SUBMITTER: Wu L 

PROVIDER: S-EPMC6866526 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature