Language network measures at rest indicate individual differences in naming decline after anterior temporal lobe resection.

ABSTRACT: While anterior temporal lobe (ATL) resection is an effective treatment for temporal lobe epilepsy, surgery on the dominant hemisphere is associated with variable decline in confrontation naming. Accurate prediction of naming impairment is critical to inform clinical decision making, and while there has been some degree of success using task-based functional MRI (fMRI) paradigms, there remains a growing interest in the predictive utility of resting-state connectivity as it allows for relatively shorter scans with low task demands. Our objective was to assess the relationship between measures of preoperative resting-state connectivity and postoperative naming change in patients following left ATL resection. We compared the resting language network connectivity of each patient to a normative

SUBMITTER: Audrain S 

PROVIDER: S-EPMC6866601 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature