Evidence-based source modeling of nociceptive cortical responses: A direct comparison of scalp and intracranial activity in humans.

ABSTRACT:

Background

Source modeling of EEG traditionally relies on interplay between physiological hypotheses and mathematical estimates. We propose to optimize the process by using evidence gathered from brain imaging and intracortical recordings.

Methods

We recorded laser-evoked potentials in 18 healthy participants, using high-density EEG. Brain sources were modeled during the first second poststimulus, constraining their initial position to regions where nociceptive-related activity has been ascertained by intracranial EEG. These comprised the two posterior operculo-insular regions, primary sensorimotor, posterior parietal, anterior cingulate/supplementary motor (ACC/SMA), bilateral frontal/anterior insular, and posterior cingulate (PCC) cortices.

Results

The model yielded

SUBMITTER: Bradley C 

PROVIDER: S-EPMC6866722 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature