Corticostriatal connectivity fingerprints: Probability maps based on resting-state functional connectivity.

ABSTRACT: Over the last decade, structure-function relationships have begun to encompass networks of brain areas rather than individual structures. For example, corticostriatal circuits have been associated with sensorimotor, limbic, and cognitive information processing, and damage to these circuits has been shown to produce unique behavioral outcomes in Autism, Parkinson's Disease, Schizophrenia and healthy ageing. However, it remains an open question how abnormal or absent connectivity can be detected at the individual level. Here, we provide a method for clustering gross morphological structures into subregions with unique functional connectivity fingerprints, and generate network probability maps usable as a baseline to compare individual cases against. We used connectivity metrics derived from

SUBMITTER: Jaspers E 

PROVIDER: S-EPMC6866797 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature