Modular-level alterations of structure-function coupling in schizophrenia connectome.

ABSTRACT: Convergent evidences have revealed that schizophrenia is associated with brain dysconnectivity, which leads to abnormal network organization. However, discrepancies were apparent between the structural connectivity (SC) and functional connectivity (FC) studies, and the relationship between structural and functional deficits in schizophrenia remains largely unknown. In this study, resting-state functional magnetic resonance imaging and structural diffusion tensor imaging were performed in 20 patients with schizophrenia and 20 matched healthy volunteers (patients/controls = 19/17 after head motion rejection). Functional and structural brain networks were obtained for each participant. Graph theoretical approaches were employed to parcellate the FC networks into functional modules. The relati

SUBMITTER: Sun Y 

PROVIDER: S-EPMC6867028 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature