Integration of white matter network is associated with interindividual differences in psychologically mediated placebo response in migraine patients.

ABSTRACT: Individual differences of brain changes of neural communication and integration in the modular architecture of the human brain network exist for the repeated migraine attack and physical or psychological stressors. However, whether the interindividual variability in the migraine brain connectome predicts placebo response to placebo treatment is still unclear. Using DTI and graph theory approaches, we systematically investigated the topological organization of white matter networks in 71 patients with migraine without aura (MO) and 50 matched healthy controls at three levels: global network measure, nodal efficiency, and nodal intramodule/intermodule efficiency. All patients participated in an 8-week sham acupuncture treatment to induce analgesia. In our results, 30% (n = 21) of patients ha

SUBMITTER: Liu J 

PROVIDER: S-EPMC6867162 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature