Automated segmentation of the human hippocampus along its longitudinal axis.

ABSTRACT: The human hippocampal formation is a crucial brain structure for memory and cognitive function that is closely related to other subcortical and cortical brain regions. Recent neuroimaging studies have revealed differences along the hippocampal longitudinal axis in terms of structure, connectivity, and function, stressing the importance of improving the reliability of the available segmentation methods that are typically used to divide the hippocampus into its anterior and posterior parts. However, current segmentation conventions present two main sources of variability related to manual operations intended to correct in-scanner head position across subjects and the selection of dividing planes along the longitudinal axis. Here, our aim was twofold: (1) to characterize inter- and intra-rate

SUBMITTER: Lerma-Usabiaga G 

PROVIDER: S-EPMC6867285 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature