NODDI reproducibility and variability with magnetic field strength: A comparison between 1.5 T and 3 T.

ABSTRACT: Diffusion models are advantageous for examining brain microstructure non-invasively and their validation is important for transference into the clinical domain. Neurite Orientation Dispersion and Density Imaging (NODDI) is a promising model for estimating multiple diffusion compartments from MRI data acquired in a clinically feasible time. As a relatively new model, it is necessary to examine NODDI under certain experimental conditions, such as change in magnetic field-strength, and assess it in relation to diffusion tensor imaging (DTI), an established model that is largely understood by the neuroimaging community. NODDI measures (intracellular volume fraction, ν_ic , and orientation distribution, OD) were compared with DTI at 1.5 and 3 T data in healthy adults in whole-brain ti

SUBMITTER: Chung AW 

PROVIDER: S-EPMC6867430 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature