Association of clinical factors with survival outcomes in laryngeal squamous cell carcinoma (LSCC).

ABSTRACT:

Aim

Treatment strategies in laryngeal squamous cell cancer (LSCC) straddle the need for long term survival and tumor control as well as preservation of laryngeal function as far as possible. We sought to identify prognostic factors affecting LSCC outcomes in our population.

Methods

Clinical characteristics, treatments and survival outcomes of patients with LSCC were analysed. Baseline comorbidity data was collected and age-adjusted Charlson Comorbidity Index (aCCI) was calculated. Outcomes of overall survival (OS), progression-free survival (PFS) and laryngectomy-free survival (LFS) were evaluated.

Results

Two hundred and fifteen patients were included, 170 (79%) underwent primary radiation/ chemoradiation and the remainder upfront surgery with adjuvant therapy where

SUBMITTER: Fong PY 

PROVIDER: S-EPMC6867599 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature