Brain development during adolescence: A mixed-longitudinal investigation of cortical thickness, surface area, and volume.

ABSTRACT: What we know about cortical development during adolescence largely stems from analyses of cross-sectional or cohort-sequential samples, with few studies investigating brain development using a longitudinal design. Further, cortical volume is a product of two evolutionarily and genetically distinct features of the cortex - thickness and surface area, and few studies have investigated development of these three characteristics within the same sample. The current study examined maturation of cortical thickness, surface area and volume during adolescence, as well as sex differences in development, using a mixed longitudinal design. 192 MRI scans were obtained from 90 healthy (i.e., free from lifetime psychopathology) adolescents (11-20 years) at three time points (with different MRI scanners u

SUBMITTER: Vijayakumar N 

PROVIDER: S-EPMC6867680 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature