Association between the TOX3 rs3803662 C>T polymorphism and recurrent miscarriage in a southern Chinese population.

ABSTRACT:

Background

Studies have shown that some genetic polymorphisms associated with breast cancer susceptibility may also be associated with abortion. The TOX3 gene plays a key role during the onset of breast cancer, and reproductive factors such as abortion are risk factors for breast cancer. However, there is currently no study describing the relationship between the TOX3 rs3803662 C>T polymorphism and the risk of recurrent miscarriage. Therefore, we investigated whether the TOX3 rs3803662 C>T polymorphism is associated with recurrent miscarriage susceptibility in this case-control study.

Methods

We recruited 248 recurrent miscarriage patients and 392 healthy controls from the southern Chinese population and performed genotyping using the TaqMan method.

Results

The result

SUBMITTER: Huang W 

PROVIDER: S-EPMC6868414 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature