Examining the relationship between household air pollution and infant microbial nasal carriage in a Ghanaian cohort.

ABSTRACT:

Background

Pneumonia, a leading cause of childhood mortality, is associated with household air pollution (HAP) exposure. Mechanisms between HAP and pneumonia are poorly understood, but studies suggest that HAP may increase the likelihood of bacterial, instead of viral, pneumonia. We assessed the relationship between HAP and infant microbial nasal carriage among 260 infants participating in the Ghana Randomized Air Pollution and Health Study (GRAPHS).

Methods

Data are from GRAPHS, a cluster-randomized controlled trial of cookstove interventions (improved biomass or LPG) versus the 3-stone (baseline) cookstove. Infants were surveyed for pneumonia during the first year of life and had routine personal exposure assessments. Nasopharyngeal swabs collected from pneumonia cases (n 

SUBMITTER: Carrion D 

PROVIDER: S-EPMC6868532 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature