C-Reactive Protein to Albumin Ratio in Colorectal Cancer: A Meta-Analysis of Prognostic Value.

ABSTRACT:

Background

The relationship between pretreatment C-reactive protein to albumin ratio (CAR) and colorectal cancer (CRC) prognosis has been extensively studied in various tumors. However, little is known on CAR and its association with prognosis in CRC. This study aims to investigate the prognostic value of pretreatment CAR in CRC.

Methods

We conducted a systematic search of MEDLINE, EMBASE, and Cochrane Library databases for eligible studies evaluating the associations of CAR with survival and/or clinicopathology of CRC. Overall survival (OS), disease-free survival (DFS), relapse-free survival (RFS), and clinicopathological features were synthesized and compared.

Results

Nine studies including 3431 patients were analyzed in this meta-analysis. Pooled results showed tha

SUBMITTER: Zhou QP 

PROVIDER: S-EPMC6868585 | biostudies-literature | 2019 Oct-Dec

REPOSITORIES: biostudies-literature