Why physiology will continue to guide the choice between balanced crystalloids and normal saline: a systematic review and meta-analysis.

ABSTRACT:

Background

Crystalloids are the most frequently prescribed drugs in intensive care medicine and emergency medicine. Thus, even small differences in outcome may have major implications, and therefore, the choice between balanced crystalloids versus normal saline continues to be debated. We examined to what extent the currently accrued information size from completed and ongoing trials on the subject allow intensivists and emergency physicians to choose the right fluid for their patients.

Methods

Systematic review and meta-analysis with random effects inverse variance model. Published randomized controlled trials enrolling adult patients to compare balanced crystalloids versus normal saline in the setting of intensive care medicine or emergency medicine were included. The main

SUBMITTER: Zwager CL 

PROVIDER: S-EPMC6868741 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature