Immunomodulatory and anti-inflammatory effects of probiotics in multiple sclerosis: a systematic review.

ABSTRACT: Multiple sclerosis (MS) is an inflammatory and autoimmune neurological disorder which leads to demyelination. Although the etiology of MS is yet to be known, it appears that regulating the immune system and suppressing inflammatory pathways may possibly have a favorable effect on the healing of this disease. Evidence suggests that probiotics consumption via gut microbiome alteration devises beneficial effects in improving immune and inflammatory responses in MS. All articles were systematically searched (in the main databases) for this paper. Two investigators independently scrutinized full texts of the potentially eligible articles. The quality of the study was evaluated using standardized tools. The methodological quality of seven studies included in this review ranged from fair to good.

SUBMITTER: Morshedi M 

PROVIDER: S-EPMC6868771 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature