Long noncoding RNAs in lipid metabolism: literature review and conservation analysis across species.

ABSTRACT:

Background

Lipids are important for the cell and organism life since they are major components of membranes, energy reserves and are also signal molecules. The main organs for the energy synthesis and storage are the liver and adipose tissue, both in humans and in more distant species such as chicken. Long noncoding RNAs (lncRNAs) are known to be involved in many biological processes including lipid metabolism.

Results

In this context, this paper provides the most exhaustive list of lncRNAs involved in lipid metabolism with 60 genes identified after an in-depth analysis of the bibliography, while all "review" type articles list a total of 27 genes. These 60 lncRNAs are mainly described in human or mice and only a few of them have a precise described mode-of-action. Because t

SUBMITTER: Muret K 

PROVIDER: S-EPMC6868825 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature