Short fused? associations between white matter connections, sex steroids, and aggression across adolescence.

ABSTRACT: Functional neuroimaging studies in adults show that aggression involves reduced brain communication between subcortical and cortical areas dedicated to motivation and control, respectively. Prior research indicates that sex steroid hormone production during adolescence negatively influences the rapid development of white matter connectivity between subcortical and cortical areas during adolescence and may potentiate aggression. Here, we tested this hypothesis in 258 participants between 8 and 25 years of age by using Diffusion Weighted Imaging to examine the microstructure of white matter connections within the fronto-temporal-subcortical network. Trait aggression was measured using the Buss Perry Aggression Questionnaire and testosterone and estradiol levels were measured in saliva. Resul

SUBMITTER: Peper JS 

PROVIDER: S-EPMC6869636 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature