Modulating cortico-striatal and thalamo-cortical functional connectivity with transcranial direct current stimulation.

ABSTRACT: Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that has been shown to alter cortical excitability and activity via application of weak direct currents. Beyond intracortical effects, functional imaging as well as behavioral studies are suggesting additional tDCS-driven alterations of subcortical areas, however, direct evidence for such effects is scarce. We aimed to investigate the impact of tDCS on cortico-subcortical functional networks by seed functional connectivity analysis of different striatal and thalamic regions to prove tDCS-induced alterations of the cortico-striato-thalamic circuit. fMRI resting state data sets were acquired immediately before and after 10 min of bipolar tDCS during rest, with the anode/cathode placed over the left pr

SUBMITTER: Polania R 

PROVIDER: S-EPMC6870027 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature