Human neural systems underlying rigid and flexible forms of allocentric spatial representation.

ABSTRACT: Previous studies suggest the importance of medial temporal lobe, areas of parietal cortex, and retrosplenial cortex in human spatial navigation, though the exact role of these structures in representing the relations of elements within a spatial layout ("allocentric" representation) remains unresolved. Hippocampal involvement, in particular, during memory processing is affected by whether a previously formed representation is employed in a novel fashion ("flexible" usage) or in a manner comparable with how it was encoded originally ("rigid" usage). To address whether brain systems are differentially involved during flexible vs. rigid utilization of a pre-existing allocentric representation, subjects encoded the position of six different target buildings relative to a centrally located land

SUBMITTER: Zhang H 

PROVIDER: S-EPMC6870227 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature