Linearity of the fMRI response in category-selective regions of human visual cortex.

ABSTRACT: The goal of this study was to determine the linearity of the blood oxygen level-dependent (BOLD) response, as measured by functional magnetic resonance imaging (fMRI), in category-selective regions of human visual cortex. We defined regions of the temporal lobe that were selective to faces (fusiform face area, FFA) and places (parahippocampal place area, PPA). We then determined the linearity of the BOLD response in these regions to their preferred and nonpreferred stimuli. First, we tested the principle of scaling. As we increased the visibility of the stimulus, there was a corresponding linear increase in the fMRI signal in the FFA and PPA to their preferred stimulus (face and place, respectively). In contrast, responses in the FFA and PPA to the nonpreferred stimulus did not conform to

SUBMITTER: Horner AJ 

PROVIDER: S-EPMC6870614 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature