Do health professionals value genomic testing? A discrete choice experiment in inherited cardiovascular disease.

ABSTRACT: Next generation sequencing (NGS) approaches are moving from research into clinical practice. However, the optimal NGS approach in well-defined adult-onset familial diseases, such as inherited cardiovascular disease, remains unclear. We aimed to determine which attributes encouraged or discouraged the uptake of genomic tests in this context, and whether this differed by test type. We conducted a web-based discrete choice experiment in health professionals in the UK who order NGS tests for inherited cardiovascular disease. Respondents completed 12 hypothetical choice tasks in which they selected a preferred test from four alternatives: whole genome sequencing, whole exome sequencing, panel testing and genetic testing not indicated. Tests were specified in terms of five attributes: diagnostic

SUBMITTER: Buchanan J 

PROVIDER: S-EPMC6870981 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature