Heritability of human visual contour integration-an integrated genomic study.

ABSTRACT: Contour integration, a key visual function to deal with occlusion and discontinuity in natural scenes, is essential to human survival. However, individuals are not equally well equipped with this ability. In particular, contour integration deficiencies are commonly detected in patients with mental disorders, especially schizophrenia. To understand the underlying sources of these individual differences, the current study investigated the genetic basis of contour integration in humans. A total of 2619 normal participants were tested on their ability to detect continuous contours embedded in a cluttered background. Quantitative genomic analysis was performed, involving heritability estimation based on single nucleotide polymorphisms (SNPs) and association testing at SNP, gene, and pathway lev

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC6871533 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature