An odorant receptor from Anopheles gambiae that demonstrates enantioselectivity to the plant volatile, linalool.

ABSTRACT: Insects express chemical receptors within sensory neurons that are activated by specific cues in the environment, thereby influencing the acquisition of critical resources. A significant gap in our current understanding of insect chemical ecology is defining the molecular mechanisms that underlie sensitivity to plant-emitted volatiles. Linalool is a commonly-occurring monoterpene that has various effects on insect behavior, either acting as an attractant or a repellent, and existing in nature as one of two possible stereoisomers, (R)-(-)-linalool and (S)-(+)-linalool. In this study, we have used a cell-based functional assay to identify linalool and structurally-related compounds as ligands of Odorant receptor 29, a labellum-expressed receptor in the malaria vector mosquito, Anopheles gamb

SUBMITTER: Huff RM 

PROVIDER: S-EPMC6872167 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature